Global Gene Profiling in Human Endometrium during the Window of Implantation
نویسندگان
چکیده
منابع مشابه
Ultrastructural Modifications of Human Endometrium during the Window of Implantation
The endometrium is a highly dynamic tissue empowered with the capacity to undergo cyclic dramatic changes in response to ovarian steroid hormones, ultimately aiming to create a window of receptivity for blastocyst implantation. Intensive research has been performed to understand and establish morphological and molecular correlates of embryo implantation. However, it still remains a biological m...
متن کاملGlobal gene profiling in human endometrium during the window of implantation.
Implantation in humans is a complex process that is temporally and spatially restricted. Over the past decade, using a one-by-one approach, several genes and gene products that may participate in this process have been identified in secretory phase endometrium. Herein, we have investigated global gene expression during the window of implantation (peak E2 and progesterone levels) in well charact...
متن کاملComparative evaluation of NOTCH signaling molecules in the endometrium of women with various gynecological diseases during the window of implantation
Objective(s): NOTCH signaling pathway is well known for its role in cell fate, cell survival, cell differentiation, and apoptosis. Some of the NOTCH signaling genes are critical for endometrial function and implantation in animals and appear to play a similar role in humans. The purpose of the current study was to investigate the potential roles of some main components of the NOTCH family in hu...
متن کاملIn search of candidate genes critically expressed in the human endometrium during the window of implantation.
BACKGROUND In this prospective randomized blinded clinical trial, we examined gene expression profiles of the human endometrium during the early and mid-luteal phases of the natural cycle. METHODS An endometrial biopsy was performed on day 16 (LH +3) or on day 21 (LH +8), followed by RNA extraction and microarray analysis using an Affymetrix HG-U95A microchip. Data analysis was carried out us...
متن کاملS100P Expression in response to sex steroids during the implantation window in human endometrium
BACKGROUND S100P, a protein originally detected in the human placenta, has been found to play an important role in the development and invasion of tumors. Interestingly, we have recently discovered using data mining that S100P was considerably up-regulated during the window of implantation in the human endometrium, but little further information has been available. METHODS Real-time PCR and i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrinology
سال: 2002
ISSN: 0013-7227
DOI: 10.1210/en.143.6.2119